21. (E)
Question type: Explain a Result
The discrepancy here is that most people who ate seafood at the particular restaurant did not come into contact with the illness causing bacteria, but that those who got this illness causing bacteria got it by eating seafood at the particular restaurant. We need an answer that resolves this discrepancy.
Answer choice (E) does just that. If one particular dish, and only that dish, had the harmful bacteria, it would make sense that some (those who ate that dish) got ill, but most (who ate other seafood dishes) did not.
(A) does not resolve the discrepancy because the discrepancy has to do with being in contact with the bacteria, not getting sick from it.
(B) does not strengthen or weaken the claim that the bacteria was from the seafood.
(C) does not explain the discrepancy.
(D) does not explain the discrepancy.